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Low-Dose Hypomethylating Agents for Myelodysplastic Syndromes (MDS)
Low-dose hypomethylating agents offer promising, well-tolerated disease control for low-risk myelodysplastic syndromes. Recent trials show decitabine achieves a 67% response rate versus 48% for azacitidine, frequently restoring transfusion independence. With a median overall survival of 33 months, low-dose therapy presents a valuable alternative for low-intermediate risk patients.
Cancer · Cancer Biology · Drug Repurposing and Off-label Use
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